Methacholine challenge in preschool children: methacholine-induced wheeze versus transcutaneous oximetry
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چکیده
منابع مشابه
Methacholine challenge in preschool children: methacholine-induced wheeze versus transcutaneous oximetry.
Tracheal/chest auscultation for wheeze and transcutaneous oximetry have both been suggested as measures of outcome in bronchial provocation tests in young children. This study aimed to compare the sensitivity and safety of these two techniques as end-points for methacholine challenge in children aged <4 yrs. Seventy-two methacholine challenges were performed in 39 children aged <4 yrs with recu...
متن کاملMethacholine bronchial provocation measured by spirometry versus wheeze detection in preschool children
BACKGROUND Determination of PC20-FEV1 during Methacholine bronchial provocation test (MCT) is considered to be impossible in preschool children, as it requires repetitive spirometry sets. The aim of this study was to assess the feasibility of determining PC20-FEV1 in preschool age children and compares the results to the wheeze detection (PCW) method. METHODS 55 preschool children (ages 2.8-6...
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Enhanced negative volume dependence of airway resistance is associated with bronchoconstriction in tracheostomized paralysed open-chest animals. Significant upper airways responses may be associated with bronchoconstriction and could thereby alter the pattern of volume dependence in spontaneously breathing subjects. The aim of the study was to test whether volume dependence of respiratory resis...
متن کاملRepeatability of methacholine challenge in asthmatic children measured by change in transcutaneous oxygen tension.
BACKGROUND The airway response to bronchial provocation may be evaluated by monitoring the fall in transcutaneous oxygen tension (PtcO2) but the repeatability of this method has not been rigorously assessed. METHODS To determine the repeatability of this indirect method of assessment, bronchial challenge was performed with methacholine in nine children with stable asthma (age range 6-12 years...
متن کاملConflicting methacholine challenge tests.
An 11-year-old boy experienced almost daily wheezing, dyspnea on exertion, and sleep perturbation because of cough. In addition, nadir peak expiratory flow (PEF) was below 100 L/min, which was 30% of predicted (328 L/min),1 compatible with severe persistent asthma.2 After the initiation of therapy with 180 g of albuterol 3 times per day, the patient’s domiciliary PEF rose to 200 L/min and his s...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1999
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.99.14511759